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Welcome to the Foundation for Angelman Syndrome Therapeutics

We have one goal: to cure Angelman syndrome.

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Scholarships open June 2nd • Registration opens Aug 1st!

Save the Date: 18th FAST Global Science Summit & Gala on Nov 7-8, 2025 – click to learn more!

Allyson Berent speaking at the FAST Global Science Summit & Gala
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For Families & Caregivers Learn More

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For Researchers Learn More

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For Industry Learn More

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For Donors Learn More

Not sure where to go? Start Here

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What is
Angelman Syndrome?

Angelman syndrome (AS) is a rare genetic condition that affects the nervous system, leading to challenges with movement, balance, and communication. It is caused by changes to chromosome 15, which impact brain function.

Learn More

FAST Angelman Syndrome News

Oak Hill Bio to continue the development of rugonersen, an investigational ASO previously owned by Roch...

CAN Spotlight: Bike 4 Briar Starts May 27th!

FAST-funded researcher highlights the involvement of UBE3A in different neurodegenerative diseases

Progress for Angelman Syndrome Relies on a Strong NIH and FDA

IONIS REVEAL Phase 3 Clinical Trial Update

Exciting Announcement: Launch of Our New Electronic Journal

Community Update: New Insights into Health and Prevention in Angelman Syndrome

The Economic Burden of Caring for Individuals with Angelman Syndrome

CAN Spotlight: Matthew Gocker continues to support AS Family in Wisconsin!

Introducing the Angelman Syndrome Global Community Advisory Board (CAB)

International Angelman Day 2025: Round-Up

FAST Italy Hosts Its First Scientific Symposium on Angelman Syndrome

FAST Poland Organized the 1st Polish National Angelman Syndrome Conference

A high sensitivity assay of UBE3A ubiquitin ligase activity from Dr. Albert Keung’s Lab

2025 AS Congressional Advocacy Day: Legislative Priorities

FAST announces the launch of two biotech companies to advance investigational gene-targeted therapies f...

February 2025: Advocacy updates and actions to take

CAN Spotlight: Raye’s Birthday Fundraiser

FAST-Affiliated Research Program at UCLA is awarded $5.8M to advance gene therapy for Angelman syndrome.

CAN Community Spotlight: Joelene

Oak Hill Bio to continue the development of rugonersen, an investigational ASO previously owned by Roch...

CAN Spotlight: Bike 4 Briar Starts May 27th!

FAST-funded researcher highlights the involvement of UBE3A in different neurodegenerative diseases

Progress for Angelman Syndrome Relies on a Strong NIH and FDA

IONIS REVEAL Phase 3 Clinical Trial Update

Exciting Announcement: Launch of Our New Electronic Journal

Community Update: New Insights into Health and Prevention in Angelman Syndrome

The Economic Burden of Caring for Individuals with Angelman Syndrome

CAN Spotlight: Matthew Gocker continues to support AS Family in Wisconsin!

Introducing the Angelman Syndrome Global Community Advisory Board (CAB)

International Angelman Day 2025: Round-Up

FAST Italy Hosts Its First Scientific Symposium on Angelman Syndrome

FAST Poland Organized the 1st Polish National Angelman Syndrome Conference

A high sensitivity assay of UBE3A ubiquitin ligase activity from Dr. Albert Keung’s Lab

2025 AS Congressional Advocacy Day: Legislative Priorities

FAST announces the launch of two biotech companies to advance investigational gene-targeted therapies f...

February 2025: Advocacy updates and actions to take

CAN Spotlight: Raye’s Birthday Fundraiser

FAST-Affiliated Research Program at UCLA is awarded $5.8M to advance gene therapy for Angelman syndrome.

CAN Community Spotlight: Joelene

Disclaimer

This website contains information for a broad audience and may include information on current and upcoming programs that are not yet approved or accessible The information provided is for general informational purposes only and is not intended as medical advice, diagnosis, or treatment. While FAST strives to provide accurate and up-to-date information, the content on this site may not always reflect the most current research or clinical guidelines. The inclusion of clinical trial information, treatments or specific healthcare providers does not imply endorsement, recommendation or guarantee of safety, efficacy, or availability. Reliance on any information provided by this website is solely at your own risk. FAST disclaims any liability for any errors or omissions in the information provided or for any decisions made based on this information. For personalized medical advice or specific health concerns including participation in any clinical trial, please consult a qualified healthcare professional.