Learn more about the four Pillar 3 programs
Pillar 3 programs: Exogenous ketone supplements, GABAaɑ5 positive allosteric modulator (Alogabat), IGF-1, 2 ligands (NNZ-2591), BDNF, in front of a building with three pillars

Pillar 3 of the FAST Roadmap to a Cure 2.0 consists of therapeutic programs which focus on “downstream targets to treat symptoms” by addressing different molecular pathways and effector proteins impacted by the missing UBE3A protein.

Currently, we have four programs in the pipeline under Pillar 3 and one active human clinical trial: