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MavriX Bio MVX-220 Update

FDA Fast Track Designation

MavriX Bio announced that that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for MVX-220, an investigational adeno-associated virus (AAV) gene therapy for the treatment of Angelman syndrome. Read the press release.

New Clinical Trial

ASCEND-AS is now listed on ClinicalTrials.gov, a Phase 1/2 first-in-human clinical study of MVX-220 in Angelman syndrome that will evaluate safety and tolerability as well as clinical efficacy assessments. (Clinicaltrials.gov ID: NCT07181837)

MVX-220 Webinar

A community webinar will be held on October 9, 2025 at 1pm ET. This webinar will be jointly hosted by FAST and ASF to provide details about the upcoming trial. MavriX will provide a summary of the trial design, requirements, and enrollment criteria.

Register for the webinar and submit your questions: https://us02web.zoom.us/webinar/register/WN_YgtRsvq6QTWNgs4sSW7yxA

Disclaimer

This website contains information for a broad audience and may include information on current and upcoming programs that are not yet approved or accessible The information provided is for general informational purposes only and is not intended as medical advice, diagnosis, or treatment. While FAST strives to provide accurate and up-to-date information, the content on this site may not always reflect the most current research or clinical guidelines. The inclusion of clinical trial information, treatments or specific healthcare providers does not imply endorsement, recommendation or guarantee of safety, efficacy, or availability. Reliance on any information provided by this website is solely at your own risk. FAST disclaims any liability for any errors or omissions in the information provided or for any decisions made based on this information. For personalized medical advice or specific health concerns including participation in any clinical trial, please consult a qualified healthcare professional.