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Home/Industry/First patient dosed in pivotal Phase 3 REVEAL clinical study of ION582 in Angelman syndrome

First patient dosed in pivotal Phase 3 REVEAL clinical study of ION582 in Angelman syndrome

Ionis Pharmaceuticals today announced that the first participant has been dosed in the global Phase 3 REVEAL study, which is designed to evaluate the efficacy and safety of ION582, an investigational medicine for the treatment of people living with Angelman syndrome (AS), a serious and rare neurodevelopmental disorder that leads to significant physical and cognitive impairments.

Ionis Press Release

Community Letter

Community Webinar on April 2025

If you have questions about trial sites or participation, please reach out directly to Ionis at (844) 285-7172 or IonisION582-CS2@clinicaltrialmedia.com

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