$64M+ Invested in Research and Development
26 Potential therapeutic programs
13 FAST-funded Programs
22 Countries connected
When FAST was founded in 2008, promising Angelman syndrome research faced significant barriers to becoming potential treatments.
Families understood that scientific promise alone would not lead to treatments. They created FAST to actively drive the work forward, bringing the urgency, resources, and determination needed to advance research toward therapeutic development.
Today, the landscape looks very different. FAST has helped advance therapeutic programs, create new pathways for drug development, and build the research tools, partnerships, and infrastructure needed to bring promising science closer to meaningful treatments.
How FAST is Changing Angelman Syndrome Research
FAST’s impact extends beyond funding scientific discoveries. From advancing therapeutic programs to building the tools needed for clinical trials, FAST has helped address critical gaps in research and development while ensuring families have a role in shaping what comes next.
Scientific Promise is Becoming Therapeutic Momentum
Guided by the Roadmap to a Cure and backed by more than $64M invested in research grants and mission-aligned investments, FAST helps promising discoveries take the critical steps toward therapeutic development.
First In-Human Progress
FAST-funded research helped bring two groundbreaking therapeutic approaches into human clinical trials for the first time, including the first investigational gene therapy.
A Broader Therapeutic Pipeline
Leading Scientists Join the Work
A New Model for Therapeutic Development
Impact Beyond Angelman Syndrome
The Field Can Measure, Study, and Prepare in Ways It Could Not Before
FAST has built the tools, data, and clinical capacity to design stronger studies and accelerate progress.
A Clearer Way to Measure Progress
A Brain Trust for Angelman Syndrome
Long-Term Data for Better Studies
Families Have a Stronger Voice in What Comes Next
Families and caregivers understand what meaningful change could look like for their loved ones living with Angelman syndrome.
FAST helps bring that experience into research, regulatory, and policy conversations while giving families trusted guidance as the science moves forward.
Daily Life Becomes Regulatory Evidence
Angelman Syndrome Has a Voice on Capitol Hill
A Stronger Voice in Regulatory Decisions
Angelman Syndrome Progress Is Now Globally Connected
FAST helps connect families, affiliates, researchers, advocates, fundraisers, and partners across borders so Angelman syndrome progress is not limited by geography.
A Growing Global Network
A Global Voice in What Comes Next
Global Family Data for Research
The Reason This Work Matters
Behind every program, tool, partnership, and investment is a family waiting for progress to reach the people they love.
For families facing Angelman syndrome, research is not abstract. It is connected to communication, sleep, seizures, movement, learning, independence, and quality of life. It is connected to the hope that tomorrow can look different than today.
That is why FAST’s work is built around urgency. Not urgency for its own sake, but urgency in service of the people and families waiting for meaningful progress.
From Progress to Possibility
Behind every milestone is a family waiting for progress to become something real.
FAST’s impact is measured by what that progress makes possible: more therapeutic paths, stronger research tools, deeper clinical readiness, greater visibility with decision-makers, and a global community moving with urgency and purpose.
There is still more work ahead. But Angelman syndrome research is no longer where it once was, and FAST is working to keep that progress moving.
Find Your Role in What Comes Next
Different people come to FAST for different reasons. Whether you are here to give, learn, connect, or partner, your next step can help keep Angelman syndrome progress moving.
If you are considering a gift
Your support helps fund the research, tools, data, infrastructure, and partnerships needed to move promising science forward.
If you are newly diagnosed
You are not doing this alone. FAST can help you find trusted information, connect with other families, and understand the research progress shaping the future of Angelman syndrome.
If you are here for the science
Angelman syndrome research is moving faster than ever. See where the field stands today and how FAST helps turn scientific promise into therapeutic momentum.
If you are a researcher, clinician, or industry partner
FAST helps build the tools, data, funding pathways, and global connections that reduce uncertainty and strengthen decision-making across Angelman syndrome research.