FAST Spain: The Dream Team

FAST España wrist bands

“Mom, don’t worry, I have come with a syndrome and the cure. It is on this path that I want you to be at my side.” Casilda Cebrián awoke in the middle of the night realizing it had been a dream. She was at the NICU next to her eight month old son, Anton, whom […]

Welcome FAST Latin America PART 1: FAST Argentina and FAST Colombia

FAST Argentina & FAST Colombia at Gala

Welcome FAST Latin America PART 1: FAST Argentina and FAST Colombia About 1 in 15,000-20,000 individuals have Angelman syndrome (AS). Latin America is home to 652 million people. That means there are about 42,000 people living with AS throughout Latin America. According to FAST Latin America (LatAm) there are, in fact, only about 1,600 families […]

Virtually Unstoppable: A Global Experience

FAST is Global

This year’s virtual Summit & Gala has proven that FAST truly is global. Over 1,700 people from 61 countries around the world tuned in to FAST’s Virtually Unstoppable Global Summit & mini-Gala. Friday’s Science Summit viewers in Japan watched the keynote speaker, Dr David Meeker, at midnight. Angelman parents in Lebanon and France joined, “lunch […]

The Next Frontier in FAST Funded Research

For 12 years FAST has been working diligently to fundraise, identify research opportunities, and wisely invest in science in order to develop real and effective treatments for our loved ones living with Angelman syndrome (AS). Thanks to your fundraising dollars, FAST has funded important pre-clinical work, developed much-needed outcome measures, and played an integral role […]

FAST Italy: educating the Italian community and contributing to global research

albert keung

Benedetta Sirtori with son Pier Luigi Today, FAST Italy is proud that their country’s first clinical trial for Angelman syndrome (AS), Roche’s Tangelo trial, is currently enrolling patients for a Phase 1 study! Nearly four years ago, when Benedetta Sirtori’s son Pier Luigi was diagnosed with AS, a treatment was unheard of. At that time, […]

FAST Australia – Building Community and Finding a Cure

FAST Aus Article

FAST Australia, one of the first branches of FAST, was founded in 2010 by a group of determined and dedicated parents of children with Angelman syndrome (AS) led by Meagan Cross and Jennifer Kyriacou. In 2008, after months of searching for answers, at 13 months of age Meagan’s second child, Molly was diagnosed with AS. […]

Diagnosis, an odyssey in developing countries

casa angelman

FAST collaborates with Casa Angelman on quest to provide diagnostic services throughout Argentina and South America As FAST continues to grow, we are fortunate to support programs, both on a national and international level. FAST will be providing funding for Casa Angelman’s genetic diagnosis campaign across Argentina.  “While genetic diagnosis is still a difficult path […]

Pilot Feasibility of an Enzyme Replacement Therapy for AS

FAST and FAST Canada are pleased to announce a grant to UC Davis.  David Segal, Ph.D. and his UC Davis lab have received funding to determine if enzyme replacement therapy (ERT) alleviates the symptoms of Angelman syndrome (AS) in animal models.  Individuals with Angelman syndrome lack a working copy of the UBE3A gene.  The UBE3A […]

Rodent Studies of Non-Snord 116 Paternal Ube3a Activation

FAST and FAST Canada are pleased to announce grant funding to David Segal, Ph.D. and his UC Davis lab to investigate targeting the Ube3a-AS (Ube3a Antisense Transcript) without disrupting the expression of Snord116 and Snord115.  Dr. Segal’s previously published research has shown that reduction in Ube3a-AS may also reduce expression of Snord116 and Snord115, which […]

Co-funded Grants with FAST Canada

FAST is proud to co-fund with FAST Canada two important grants, Rodent Studies of Non-Snord 116 Paternal Ube3a Activation and Pilot Feasibility of an Enzyme Replacement Therapy for AS, both from Dr David Segal’s lab at UC Davis. FAST Canada chose to co-fund these two particular grants because they wanted to focus their first funding […]