2015 FAST Summit & Gala
Becky Burdine, Ph.D. ~Introduction/Therapeutics in Angelman Syndrome
FAST FIRE Team
The most aggressive, novel, innovative research initiative whose goal is to identify treatments for Angelman Syndrome.
- Edwin Weeber, Ph.D. – Behavioral differences seen in AS, new potential outcome measures in AS and synaptic function in the AS model.
- Scott Dindot, Ph.D. – AS drug screening, mechanisms regulating imprinting of UBE3A and new animal models of AS.
- Anne Anderson, MD – Seizure and behavioral phenotypes in the AS mice and how this information will be used in preclinical trials.
- David Segal, Ph.D. – Progress in designing epigenetic regulators for persistent UBE3A activation.
- Kevin Nash, Ph.D. – Protein replacement therapy using gene delivery.
Information to clarify desirable long-term outcomes and evidence informed practices towards the development of accessible, autonomous communication for children who use AAC.
Key principles and strategies including structured shared reading, predictable chart writing, independent emergent reading and writing, and early skills instruction. The use of Core Vocabulary and Soft-Tech Reading Page Sets and how they support communication during shared reading. Decision tree for determining when emergent literacy or conventional literacy instruction is most appropriate.